The seminar will take place, the 9th of November 2017, at 2pm, at the ENSCBP amphitheater, Building B, allée Geoffroy Saint-Hilaire, Pessac.
Dr. Vladimir Torbeev
(UMR 7006 – ISIS, Université de Strasbourg)
Modern peptide ligation chemistries allow for an efficient total chemical synthesis of small and medium size proteins. Chemical strategies are inherently flexible and enable incorporation of unlimited combinations of unnatural amino acids, post-translational modifications and various labels. In combination with biophysical techniques, this approach has strong potential to contribute to better understanding of the challenging problems in protein chemistry and biology. Applications of chemical protein synthesis to dissecting mechanisms of protein misfolding and aggregation, studying structure and function of intrinsically disordered proteins and designing new catalytic proteins will be presented.
Contact: Gilles Guichard, g.guichard@cbmn.u-bordeaux.fr
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